GEMS Launcher
Introduction
GEMS Launcher offers the technology to assess the functional structure of genomic sequences by an integrated collection of tasks tailored to the actual needs of research in functional genomics.
The philosophy is to offer biologists a sophisticated, comprehensive and easy-to-use software package for DNA analysis. GEMS Launcher combines the power of several popular Genomatix tools that have set standards in bioinformatics software in the last decade (e.g. MatInspector, ModelInspector, DiAlign).
GEMS Launcher integrates highest quality databases and gold standard algorithms for in-depth analysis of transcriptional regulation. The tasks are divided into the following categories:
- Transcription factor binding sites
- Complex regulatory patterns
- Alignment
- Miscellaneous
- Genomatix sequence tools
Discover the molecular mechanisms of gene regulatory networks with GEMS Launcher:
- MatInspector:
Search for transcription factor binding sites in any sequence - MatDefine:
Generate and validate your own positional weight matrices for transcription factor binding sites - CoreSearch:
Define unknown regulatory patterns - FrameWorker:
Identify complex regulatory patterns within promoters and enhancers - FastM:
Define your own high-order modules of sequence organisation - ModelInspector:
Scan complete genomic databases for common promoter organisation (see Promoter Module Library) - SequenceShaper:
Design site mutagenesis for generating custom regulatory sequences - SNPInspector:
Analyse sequences for effects of SNPs on regulatory elements - DiAlign:
Perform a true multiple alignment of DNA or protein sequences - DiAlign TF:
Combine alignments with transcription factor binding site information - SMARTest:
Discover potential S/MARs in your sequences - ExonMapper:
Map your cDNA sequences to genomic databases - PromoterInspector:
Predict promoters in mammalian sequences - MatBase (only included with licenses for 12 months or upwards):
The transcription factor knowledge base